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Simple and repetitive epicutaneous tests

We can investigate the tolerability of your product with a series of epicutaneous tests. This determines whether a test product causes a reaction after application to the skin. The different test designs differ, e.g., in the duration of the application phase, the test area, the type of application (open, semi-occlusive, occlusive). We also recommend appropriate designs for specific product categories.

The epicutaneous tests are usually performed on the skin of healthy test subjects. As an option, we can offer you testing on special collectives. In addition, we consider subjects with sensitive skin, depending on the respective test design. Our offering of simple and repetitive epicutaneous tests includes:

  • Open epicutaneous patch test
  • Epicutaneous Patch Test (p.e. 24h or 48h)
  • 3 x 24h Epicutaneous Patch Test
  • 15 Day Cumulative Irritation Patch Test
  • 21 Day Cumulative Irritation Patch Test
  • Soap chamber test
  • Repetitive Epicutaneuous Patch Test

Tolerability studies on pre-damaged skin

If the product is actually used by the end user on particularly sensitive skin (e.g., in the area of the mucosa or on baby skin), this must be taken into account in the test procedure. In this case, carrying out the tolerability test on intentionally damaged skin makes sense. By damaging the skin, its reactive potential to the provocation that has taken place is increased, thus placing the tolerability of the test product under intense scrutiny. We are able to damage the skin using various methods. We offer the following test designs

  • Single Epicutaneous Test
  • Shaving Irritation
  • Scratched (Scarified) Chamber Test

Dermatological use tests

The most realistic test is the dermatological-controlled use test, which evaluates the tolerability of the test product after a two-week application period. In addition to the dermatological assessment, subjective parameters such as itching, burning, and a feeling of tightness are also assessed as part of the study, and the cosmetic acceptance is evaluated.

The dermatological evaluation can be carried out by a specialist (dermatologist, pediatrician, gynecologist, ophthalmologist, dentist, ENT specialist), a general practitioner, or a trained evaluator. In addition, two test products can be investigated in a split design, and the questionnaire can be statistically evaluated. We are happy to offer additional options on request

  • with a trained evaluator
  • with a general practitioner
  • with a specialist (dermatologist, pediatrician, gynecologist, ophthalmologist, dentist, ENT specialist)

Further Tests

  • Human Repeat Insult Patch Test (HRIPT)
  • Photosensitization
  • Phototoxicity
  • Stinging Test
  • Forearm Wash Test