Research News

2018

• Compatibility Testing of Cosmetics and Toiletries for Babies and Children, A. Erlach et al.
• An updated review of clinical methods in the assessment of ageing skin – New perspectives and evaluation for claims support, S. Bielfeldt et al.
• The combined use of a nonabrasive, activator-containing toothpaste and a light emitting diode device improves the onset time of tooth whitening, S. Bielfeldt et al.
• Perspiration & Odor Testing Methods & New Opportunities for Claims Development, S. Bleckwenn, et al.

2017

• Heat protection – a sophisticated approach to assess protective efficacy against mild damage by blow-drying, I. Kruse, et al.
• Increasing the negative pressure in the model of generating standardized wounds by the method of suction blister induction, C. Wagner, et al.
• Wundheilungsmodell mit Saugblasen: Kann eine Erhöhung des Unterdrucks die Erzeugung von Saugblasen beschleunigen?, C. Wagner, et al.
• Subjectively Sensitive – Supporting Claims for Sensitive Skin, G. Springmann, et al.
• Anti-Static Effects of Hair Cosmetics – Measurable and Perceptible?, M. Brandt, et al.
• Tolerability and efficacy of sunscreen products under conditions of sweating and physical activity, S. Bielfeldt, et al.
• Image analysis parameters to quantify the healing of superficial model wounds in vivo, S. Bielfeldt, et al.
• Hautschutzstrategien gegen Umwelteinflüsse – Eine neue klinische Testmethode mit Zigarettenrauch als Modell-Schadstoff, S. Bielfeldt, et al.

• In vivo determination of sweat resistance of sun protection products, S. Bielfeldt, et al.
• In vivo methods to evaluate anti-photo aging and anti-pollution efficacy claims of cosmetic products, N. Lunau, et al.
• Models of wound healing: an emphasis on clinical studies, K. P. Wilhelm, et al.
• A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora, H. Stettler, et al.
• Testing for Anti-Pollution Skin Benefits in Human Volunteers, G. Springmann, et al.
• Improved Quantification of Skin Erythema Pattern by Color Analysis of Highly Standardized Photographic Images, M. Seise, et al.
• Penetration of Glycerin into the First Layers of Stratum Corneum measured by in vivo Raman Spectroscopy, S. Laing, et al.
• Substantiating Claims for Hair Care Products, M. Brandt, et al.
• Extrinsic Hair Aging: Cosmetic Treatment Concepts and Biophysical Test Methods, M. Brandt, et al.
• How can split ends be characterized? New parameters to assess the severity of split hairs, M. Brandt, et al.
• A plant oil-containing pH 4 emulsion improves epidermal barrier structure and enhances ceramide levels in aged skin, J. D. Blaak, D.; Dähnhardt-Pfeiffer, S.; Bielfeldt, S., K.-P., Wilhelm; Wohlfahrt, R.; Staib, P.
• Substantiating anti-pollution claims, S. Bielfeldt, et al.
• In Vivo Sweat Resistance Determination of Sun Protection Products, S. Bielfeldt, et al.
• Good measurement practice matters. Clinical sun protection product testing update S. Bielfeldt, et al.
• Environmental Skin Protection Strategies – a New Clinical Testing Method Employing a Cigarette Smoke Pollutant Model, S. Bielfeldt, et al.
• Pollution Protection and the Skin – Testing Strategies, S. Bielfeldt, et al.
• Clinical Anti-Malodour Efficacy of Experimental Toothpaste, K. Gysen, et al.
• Significant Reduction of Body Odor in Older People with a pH 4.0 Emulsion, S. Bielfeldt, et al.
• An evaluation of properties related to wear time of four dressings during a five-day period, S. Bielfeldt, et al.
• Prevention and Repair of Split Ends of Hairs: How to Evaluate?, S. Bielfeldt, et al.
• Decorative Cosmetics: In Vivo Facial Measurement of Color Parameters, Even Skin Tone and Radiance, S. Bielfeldt, et al.
• An investigation of the effect of six emollients on skin characteristics, M. Waring, et al.
• Efficacy of a New Topical Nano-hyaluronic Acid in Humans, M. Jegasothy, et al.
• Studies on the Skin Compatibility os Cosmetics Involving Human Subjects, J. Ennen, et al.
• Non Invasive Diagnostic Techniques in Clinical Dermatology, E. Berardesca, et al.
• A New Mometasone Formuation (LAS41002 Emulsion, 36% Water Content) Is Effective, Well Tolerated And Cosmetically Acceptable In The Treatment Of Scalp Psoriasis, K. P. Wilhelm, et al.
• A New Mometasone Formulation (LAS41002 Emulsion) Has Equivalent Antipsoriatic Efficacy Compared to Reference Mometasone Cream, K. P. Wilhelm, et al.
• A New Mometasone Cream Vehicle With a 33% Water Content Offers a High Cosmetic Acceptance: A Cosmetic Test Study In Healthy Volunteers, K. P. Wilhelm, et al.
• Efficacy of Restylane® Day Cream and Restylane Night Cream (containing stabilised hyaluronic acid) on skin hydration and skin structure, K. P. Wilhelm, et al.
• Short term clinical efficacy of new meridol halitosis tooth and tongue gel in combination with a tongue cleaner to reduce oral malodor, D. Wilhelm, et al.
• A new methodology for evaluating the damage to the skin barrier caused by repeated application and removal of adhesive dressings, M. Waring, et al.
• An observational cross-sectional survey of rosacea: clinical associations and progression between subtypes, J. Tan, et al.
• Improvement of skin barrier function in atopic dermatitis patients with a new moisturizer containing a ceramide precursor, E. Simpson, et al.
• Improvement of skin barrier function in atopic dermatitis patients with a new moisturizer containing a ceramide precursor, E. Simpson, et al.
• Skin Smoothing and Moisturizing Properties of a Panthenol Jojoba Spray, O. Schmidt Eckey, et al.
• A pharmacological model to evaluate the flush model in rosacea patients, L. Petit, et al.
• Compliance with RCEE Values when Determining the in vivo SPF, D. Kockott, et al.
• Skin Benefits with a Novel Emollient-Treated Menstrual Pad, M. A. Farage, et al.
• Comparison of the stratum corneum thickness measured in vivo with confocal Raman spectroscopy and confocal reflectance microscopy, A. Bohling, et al.
• Chances and limits of an improved method to assess water resistance of cosmetic sunscreen products in vitro on polymethylmethacrylate plates, S. Bielfeldt, et al.
• Internet-based lay person rating of facial photographs to assess effects of a cleansing product and a decent cosmetic foundation on the attractiveness of female faces, S. Bielfeldt, et al.
• Assessment of hair breakage from combing: Which procedure simulates best the true life situation?, S. Bielfeldt, et al.
• Dermatotoxicology, K. P. Wilhelm, et al.
• Imaging techniques, why, when and which?, K. P. Wilhelm
• Clinical efficacy of a new tooth and tongue gel applied with a tongue cleaner in reducing oral halitosis, D. Wilhelm, et al.
• An instant tack wound dressing designed to reduce skin stripping, M. Waring, et al.
• Skin exposure to deodorants/antiperspirants in aerosol form, W. Steiling, et al.
• Color-consistent clinical photography in dermatological studies, M. Seise, et al.
• Improvement of image analysis of dermatological images by utilizing intelligent scissors, M. Seise, et al.
• In vivo and in vitro SPF Determination – two sides of the same coin?, M. Rohr, et al.
• A review of the effects of moisturizers on the appearance of scars and striae, A. V. Rawlings, et al.
• Dexpanthenol modulates gene expression in skin wound healing in vivo, R. Heise, et al.
• Anti-ageing skin care conference – Nurture and Nature, J. Ferguson, et al.
• Use of modified forearm-controlled application test to evaluate skin irritation of lotion formulations, M. A. Farage, et al.
• Direct Evaluation of the Barrier Integrity by Visualization of the Intercellular Lipid Lamellae using TEM.Pilot Study with an Emollient on Children with Atopic Skin, D. Dähnhardt, et al.
• Noninvasive Stratum Corneum Sampling and Electron Microscopical Examination of Skin Barrier Integrity: Pilot Study with a Topical Glycerin Formulation for Atopic Dermatitis, S. Daehnhardt-Pfeiffer, et al.
• Hold of decorative comsetics determined by lay and expert rating and image analysis, M. Brandt, et al.
• An integrated process for clinical photography, A. Böhling, et al.
• Ranking of paired standardized facial photographs to evaluate attractiveness and skin radiance, S. Bielfeldt, et al.
• Lack of irritative potential of nadifloxacin 1% when combined with other topical anti-acne agents, K. P. Wilhelm, et al.
• An evaluation of the skin stripping of wound dressing adhesives, M. Waring, et al.
• A Clinical Picture of Rosacea: Description of a Panel of 130 Rosacea Patients recruited in Hamburg, Germany, M. Guyomar, et al.
• Dermatological testing of an improved apertured film surface for feminine hygiene pads, M. A. Farage, et al.
• Anti-aging data and support claims – Consensus statement, P. Elsner, et al.
• Cream or foam in pedal skin care: towards the ideal vehicle for urea used against dry skin, C. Borelli, et al.
• Advances in Measuring the Water Content of Dry Skin by In-Vivo Confocal Raman Spectroscopy, A. Böhling, et al.
• Bioengineering methods to assess aging parameters in the depth of the skin, S. Bielfeldt, et al.

• Functional food, food supplements and the skin, K. P. Wilhelm, et al.
• Efficacy of a new mouthrinse formulation on the reduction of oral malodor in vivo. A randomized, double-blind, placebo-controlled, 3 week clinical study, W. Wigger-Alberti, et al.
• In vitro sun protection factor: Still a challenge with no final answer, M. Rohr, et al.
• Interlaboratory studies with a proposed patch test design to evaluate the irritation potential of surfactants, A. Mehling, et al.
• Hautverträglichkeit zweier ethanol-basierter Hautantiseptika und ihrer Hilfsstoffe, G. Kampf, et al.
• Comparison of the stratum corneum thickness on forearm, leg, face and palmar measured by confocal Raman spectroscopy and confocal microscopy, A. Böhling, et al.
• Nicht invasive Quantifizierung der Wirksamkeit von Anti-Cellulite-Mitteln, S. Bielfeldt
• Functional food, food supplements and the skin (special lecture), K. P. Wilhelm, et al.
• Non-invasive imaging to quantify the grade of cellulite severity (abstract), K. P. Wilhelm, et al.
• Working against halitosis – Study data, K. P. Wilhelm
• The innovator’s dilemma: biophysics and imaging of the skin. The CRO perspective (abstract), K. P. Wilhelm
• Efficacy of a polyurethane dressing versus a soft silicone sheet on hypertrophic scars, W. Wigger-Alberti, et al.
• Using a novel wound model to investigate the healing properties of products for superficial wounds, W. Wigger-Alberti, et al.
• Klinische Wirksamkeit der meridol HALITOSIS Mundspülung bei der Reduktion von Mundgeruch, W. Wigger-Alberti, et al.
• Assessment of human stratum corneum thickness and its barrier properties by in-vivo confocal Raman spectroscopy, S. Bielfeldt, et al.
• A randomized, double-blind, clinical study investigating the cumulative irritation potential of a nadifloxacin cream combined with an additional treatment of other topical anti-acne products in a 21 day open application test, W. Wigger-Alberti, et al.
• New analysis tool for sensitive discrimination of in vivo acne UV-Fluorescence photography, S. Ekanayake Mudiyanselage, et al.
• Advanced methods for investigating the grade of cellulite severity, M. Brandt, et al.
• Improvement of clinical methods to quantify the efficacy of anti-dandruff products, S. Bielfeldt, et al.
• Assessment of human stratum corneum thickness and its barrier properties by in-vivo confocal raman spectroscopy, S. Bielfeldt, et al.
• Non-invasive imaging to quantify the grade of cellulite severity, S. Bielfeldt, et al.
• Skin imaging in claims substantiation, K. P. Wilhelm, et al.
• Novel abrasive wound model to investigate the healing properties of different dressings for superficial wounds – An open-label, randomized, Intra-individual clinical study, W. Wigger-Alberti, et al.
• Cell attachment to adhesive dressings: qualitative and quantitative analysis, M. Waring, et al.
• Skin-lightening effects of a new face care product in patients with melasma, U. Scherdin, et al.
• p53 labeling index in assessing the efficacy of a sunscreen in protection against UV-induced damage, M. Lens, et al.
• A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part II: Clinical perspectives and clinical methods in the evaluation of aging skin., T. Callaghan, et al.
• A review of ageing and an examination of clinical methods in the assessment of ageing skin. Part I: Cellular and molecular perspectives of aging skin., T. Callaghan, et al.
• Objective evaluation of cosmetic claims in human volunteers, T. Callaghan, et al.
• Microrelief & wrinkle measurements, T. Callaghan, et al.
• Influence of climatic conditions on antiperspirant efficacy determined at different test areas, M. Brandt, et al.
• Non-invasive evaluation techniques to quantify the efficacy of cosmetic anti-cellulite products, S. Bielfeldt, et al.
• Challenges of non-invasive imaging in the understanding of cellulite, T. Callaghan, et al.
• Efficacy of a polyurethane dressing on hypertrophic scars in comparison to a silicone sheet, W. Wigger-Alberti, et al.
• OECD Guidelines  for testing of chemicals, K. P. Wilhelm, et al.
• Bioengineering of the skin: Skin imaging and analysis, K. P. Wilhelm, et al.
• Anwendungsbeobachtung mit einem topischen silberhaltigen Pflegeprodukt (Multilind® MikroSilber Creme) zur Überprüfung der Wirksamkeit, Verträglichkeit und kosmetischen Akzeptanz beim atopischen Ekzem, S. Ekanayake Mudiyanselage, et al.
• Noninvasive imaging in the evaluation of cellulite, T. Callaghan, et al.
• Influence of applied quantity of sunscreen products on the sun protection factor- A multicenter study organized by the DGK Task Force Sun Protection, R. Bimczok, et al.
• Non-invasive imaging of inflammatory acne lesions, S. Bielfeldt, et al.
• Implementation of a Quality Management System in a Contract Laboratory Working with Non-Invasive Methods, K. P. Wilhelm, et al.
• Fenugreek + micronutrients: Efficacy of a food supplement against hair loss, C. Schulz, et al.
• Preliminary testing for normality – A common approach critically reviewed, V. Schoder, et al.
• Preliminary testing for normality: some statistical aspects of a common concept, V. Schoder, et al.
• Do atopics tolerate alcohol-based hand rubs? A prospective, controlled, randomized double-blind clinical trial, G. Kampf, et al.
• Is cellulite an aging phenomenon?, T. Callaghan, et al.
• Methods to evaluate the benefit of acne treatment in clinical studies (P119), T. Callaghan, et al.
• Non-invasive imaging of inflammatory acne lesions (P408), T. Callaghan, et al.
• Skin imaging and cosmetic claim support: strategies for scientifically sound evaluation, S. Bielfeldt, et al.
• Use of image analysis techniques for objective quantification of the efficacy of different hair removal methods, S. Bielfeldt, et al.
• Examination of cellulite using in vivo confocal microscopy, T. Callaghan, et al.
• Clinical efficacy and skin compatibility of Eucerin® anti-age anti-pigment fluid, a novel anti-age face care fluid contaning dioic acid, K. Bohnsack, et al.
• Clinical and biophysical aspects of sensitive skin: Assessment and protection, W. Wigger-Alberti, et al.
• Sensory irritation in the facial stinging test, W. Wigger-Alberti, et al.
• Vorab-Test auf Normalverteilung – kritische Betrachtung einer gängigen Praxis, V. Schoder, et al.
• Teststrategie für Produkte für Kinder: Besonderheiten bei der Konzeption und Produktprüfung, K. P. Wilhelm
• Clinical efficacy and skin compatibility of a novel anti-pigment fluid contaning dioic acid, A. Schölermann, et al.
• Objective assessment of the efficacy of different depilation techniques by use of quantitative image analysis, S. Bielfeldt, et al.
• Untersuchungen zur Verträglichkeit von Kinder- und Babykosmetik, K. P. Wilhelm, et al.
• Transepidermal water loss and barrier function of aging human skin, K. P. Wilhelm, et al.
• Skin-lightening effects of a new face care product in patients with melasma (abstract), U. Scherdin, et al.
• Emollients in a propanol-based hand rub can significantly decrease irritant contact dermatitis, G. Kampf, et al.
• Clinical research, B. Dréno, et al.
• An examination of non-invasive imaging techniques in the analysis and review of cellulite, T. Callaghan, et al.
• Challenges, opportunities in clinical evaluations of oral beauty supplements, T. Callaghan, et al.
• Image analysis techniques for objective quantification of the efficacy of different depilation methods (abstract), S. Bielfeldt, et al.
• Clinical efficacy and skin compatibility of Eucerin® anti-age anti-pigment fluid, a novel anti-age face care fluid contaning dioic acid (abstract), K. Bohnsack, et al.
• Wirksamkeit und Verträglichkeit des kosmetischen Pflegeproduktes GEHWOL® med Lipidro Creme bei Diabetikern, S. Bielfeldt, et al.
• Evaluation of the anti-drying efficacy of high protection sunscreens after UV-irradiation (abstract), S. Bielfeldt, et al.
• Quality management in the skin bioengineering laboratory: a strategic approach (abstract), K. P. Wilhelm
• Multicentre comparison of skin hydration in terms of physical-, physiological- and product-dependent parameters by the capacity method (Corneometer CM 825), U. Heinrich, et al.
• Water resistance determination of sunscreen products: the actual status., S. Bielfeldt, et al.
• Assessment of patch test reactions due to hair dyes with the laser Doppler perfusion scanning techniques, W. Wigger-Alberti, et al.
• Mapping mechanical properties of human skin, K. P. Wilhelm, et al.
• Pesticide toxicity – Evaluation of cytotoxicity of 11 pesticides separately and in combination, K. P. Wilhelm, et al.
• Development and validation of a semi-automatic image analysis system for measuring skin desquamation with D-Squames, K. P. Wilhelm, et al.
• A skin sensitization safety assessment of a new bleach activator technology in detergent applications, R. Roggeband, et al.
• Guidelines for visualization of cutaneous blood flow by laser Doppler perfusion imaging. A report from the Standardization Group of the European Society of Contact Dermatitis based upon the HIRELADO European community project, A. Fullerton, et al.
• Bioengineering of the skin: Skin biomechanics, P. Elsner, et al.
• Immediate and short time modifications of the cutaneous surface profile investigated by rapid phase shift profilometry, S. Bielfeldt, et al.
• Behandlung trockener Hautzustände bei Hautgesunden und Personen mit atopischer Diathese, S. Bielfeldt, et al.
• The many faces of skin irritation: test strategies to evaluate skin irritation potential (abstract), K. P. Wilhelm, et al.
• Non-invasive assessment of patch test reactions due to hair dyes with the laser Doppler perfusion scanning technique, W. Wigger-Alberti, et al.
• Multiparametrische Untersuchung Detergenzien-induzierter Hautreizungen, W. Wigger-Alberti, et al.
• Comparison of three techniques for evaluating skin erythemal response for determination of sun protection factors of sunscreens: high resolution laser Doppler imaging, colorimetry and visual scoring, K. P. Wilhelm, et al.
• Quantitative assessment of primary skin irritants in vitro in a cytotoxicity model: comparison with in vivo human irritation tests, K. P. Wilhelm, et al.
• Role of flavonoids in controlling the phototoxicity of Hypericum perforatum extracts, K. P. Wilhelm, et al.
• Stimulation der epidermalen Regeneration durch 5% Dexpanthenol – Ergebnisse einer Placebo-kontrollierten Doppelblindstudie S. Presto, et al.
• Dermal and mucosal tolerance of a new antiseptic liquid soap, G. Kampf, et al.
• Scale-sensitive fractal analysis using the patchwork method for assessment of skin roughness, K. Articus, et al.
• Alpha-Glucosylrutin – An innovative topical antioxidant for prophylaxis of photodamage and polymorphous light eruption, F. Stäb, et al.
• Advanced skin caring and protecting properties of a novel antioxidant-containing sunscreen, F. Stäb, et al.
• Irritative Kontaktdermatitis, K. P. Wilhelm, et al.
• Rapid 3D in vivo imaging and measurement of skin topography, K. P. Wilhelm, et al.
• Axillary pH and influence of deodorants, S. Stenzaly-Achtert, et al.
• Wirknachweis für Deodorants und Antitranspirants, M. Keskin, et al.
• Efficacy testing of antiperspirants during early product development, S. E. Bielfeldt, et al.