Efficacy testing of antiperspirants and deodorants

Whether conducting a classic efficacy study, proof of a specific claim, or a comparative assessment of multiple formulation options in a screening – with our offering in the area of “Antiperspirants and Deodorants”, we are well prepared for the versatility of this product category and can serve a variety of testing needs. We investigate the efficacy of antiperspirants with a study design according to the FDA or Clearcast guidelines in which test subjects sweat under standardized conditions in our hot room. During this, one armpit is treated with the test product and the other remains untreated. The sweat is collected with cotton pads and the efficacy of the product determined by gravimetric comparison to the baseline.

The efficacy testing of deodorants is carried out organoleptically with the help of our ‘odor judges’ (‘sniffers’), who evaluate the smell of the sweat by sniffing the armpits of the test persons. In order to be able to present you with meaningful results, we train our “odor judges” on a continual basis. We can tailor both test methods to the specific properties of your product in terms of sweat formation. We can do this, for instance, by physical activity or by creating a stressful situation. We can also test whether your antiperspirant might leave spots behind on textiles.

Our portfolio includes:

  • proDERM Screening Method (to identify a suitable formulation)
  • Antiperspirant-Test according to FDA-Guidelines
  • Antiperspirant-Test according to Clearcast-Guidelines
  • Yellow spots on white textiles
  • White spots on dark textiles
  • Deodorant Efficacy(Sniff-Test)
  • AT / Deodorant Efficacy related to stress / physical activity

proDERM | Your partner for trustworthy clinical studies.

In Dermatology, Oral Care, Ophthalmology, Hair Care, Women’s Health and Sun Care

Qualification of ‚Odor Judges‘

Despite electronic noses that are highly sensitive to certain odor components, it is still not possible to determine the odour-reducing effects of deodorants with reliable measuring instruments. Deodorant efficacy trials will therefore continue to be conducted with the help of so-called ‘Odor Judges’ (‘Sniffers’). Odor Judges are persons with trained noses who evaluate the smell of sweat on test subjects by direct sniffing. In order to achieve reliable and reproducible study results using this method, sophisticated training of Odor Judges is essential. At proDERM, this training takes place in two stages:

In stage 1, suitable candidates are selected during a training day. Sniff-sticks with standard odor substances are used to check the suitability of candidates. They must first recognize selected odors and correctly classify a substance. If they succeed, their odor threshold is determined and their ability to differentiate between odor intensities is tested. The few remaining candidates who have demonstrated their general suitability up to this point receive training on the olfactometer in stage 2. This device enables diverse odors to be standardized for the nose and provided in precisely defined concentrations for sniffing. Odor sensitivity is determined according to DIN/EN 13725. If the candidate passes this test, systematic training follows.

Artificial sweat is blown in various dilutions into the sniffing mask so that candidates can practice distinguishing between different concentrations and estimating their intensity. The success of this training is then checked in a final intensity test with different concentrations. Only those candidates who also pass this test will be included in the trained panel of Odor Judges.

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Our latest publication related to Antiperspirants and Deodorants: ‚Perspiration and Odor Testing Methods and New Opportunities for Claims Development‘.

FactSheet

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